A, 14 dioxane ring manufacturers take you to understand what the claims of 14 dioxane ring!

1. A method for synthesizing 1, 4-dioxane - 2-ketone from ethylene glycol is characterized by: Is the synthesis of glycol monosodium, the reaction is to mix the dehydrating agent, glycol and sodium hydroxide, excessive glycol, glycol and sodium hydroxide molar ratio is greater than 1.3, after the completion of the reaction, cooling to room temperature, standing stratification, separation of the upper liquid, the upper liquid is the mixture of dehydrating agent and glycol, after adding glycol directly for the next reaction. The entrained glycol in low glycol monosodium does not need to be separated;

2. When synthesizing sodium hydroxy-ethoxyacetic acid, glycol, sodium chloroacetic acid and glycol monosodium are mixed for reaction, and the amount of sodium chloroacetic acid is equal to the amount of sodium hydroxide. After the reaction, sulfoxide was added, glycol was recovered by vacuum distillation, acetone was added after cooling, and then crude β-hydroxyethoxyacetic acid sodium was obtained by vacuum distillation and acetone was recovered. The residual liquid was sulfoxide, which was directly recovered.

3, the synthesis of 14-dioxy-hexacyclo-2-ketone, that is, adding oxy-containing heterocyclic solvent β-hydroxy-ethoxyacetic acid sodium, mixed slowly with concentrated sulfuric acid. After the reaction, desiccants were added, filtration was done, and the solvent containing heterocyclic oxygen was added for washing. The solvent containing heterocyclic oxygen was recovered by vacuum distillation, and the distillation residue was recovered by vacuum distillation. The distillate was collected to obtain 1, 4-dioxy-hexacyclo-2-one, or 1, 4-dioxy-hexacyclo-2-one was obtained by recrystallization with aliphatic esters at low temperature.